The best Side of ceesdekker
The best Side of ceesdekker
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Rotary movement of DNA rotors on nanopores. Leading row: Uncooked video clip of the Cy5 channel of every rotor. Middle row: corresponding solitary-particle localization outcomes of both finishes from the DNA rotors. The situation of the current body is marked as orange and blue dots, as well as trajectory of the 10 frames before The present body is proven as good traces.
1996, to start with mesoscopic charge density waves products; and first electrical measurements on an individual metallic nanocluster between nanoelectrodes
Multicolor imaging of the bacterial nucleoid and cell division proteins with blue, orange, and around-infrared fluorescent proteins
2007, to start with actual-time detection of strand Trade in homologous recombination by RecA; discovery of the minimal persistence size of finishes of microtubules; and resolved the mechanism of biosensing with carbon nanotubes
Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever structure in 2005. (nl)
Our study ranges within the biophysics of DNA to artificial cells and past. Be sure to take a look below within the spectrum of our recent tasks.
All parameters had been the same for every panel in this movie, except for the Original placement in the 6hb rod (revealed in blue) about the nanopore. Simulations that terminated early because of translocation with the rod throughout the pore are marked by a gray track record.
Flow-pushed rotary motors including windmills and drinking water wheels travel useful processes in human society. Whilst examples of this kind of rotary motors also function prominently in cell biology, their synthetic construction in the nanoscale has remained difficult. Here we reveal circulation-driven rotary movement of the self-structured DNA nanostructure that is definitely docked onto a nanopore in a skinny sound-state membrane. An elastic DNA bundle self-assembles right into a chiral conformation upon phoretic docking onto the good-condition nanopore, and subsequently displays a sustained unidirectional rotary movement of up to twenty rev s−1.
2003, demonstrated the main biosensors manufactured out of a carbon nanotube; solved the construction and system of DNA fix proteins; and discovery of a new strategy for fabricating strong-point out nanopores for DNA translocation
It had been for the duration of this period that Dekker carried out https://www.ceesdekker.net research on magnetic spin techniques and on sound in superconductors and semiconductors.
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2008, 1st observation of protein-coated DNA translocation by means of nanopores; resolved the origin of your electrophoretic pressure on DNA in nanopores; identified a substantial velocity increase of microtubules in electric powered fields; identified an anomalous electro-hydrodynamic orientation of microtubules; and resolved the origin of sounds in carbon nanotubes in liquid
2004, discovery of new physics in translocation of DNA by nanopores; initial experimental analyze of ions conduction in nanofluidic channels; very first electrochemistry with individual solitary-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; initial electrical docking of microtubules on kinesin-coated nanostructures; initially biophysics characterization from the mechanical Houses of double-stranded RNA; and initial solitary-molecule analyze of DNA translocation by a restriction-modification enzyme.